NFL capsule: 49ers 15-point favorites vs. Cardinals

NFL capsule: 49ers 15-point favorites vs. Cardinals
December 29, 2012, 5:15 pm
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The 49ers will hope to bounce back from a humiliating loss to the Seahawks last week and claim the NFC West title. (AP)

ARIZONA (5-10) at SAN FRANCISCO (10-4-1)

Sunday, 4:25 p.m., FOX

OPENING LINE - San Francisco by 15

RECORD VS. SPREAD - Arizona 6-8-1; San Francisco 9-6

SERIES RECORD - 49ers lead 25-17

AP PRO32 RANKING - San Francisco No. 6; Arizona No. 27

LAST MEETING - 49ers beat Cardinals 24-3, Oct. 29

LAST WEEK - 49ers lost to Seahawks 42-13; Cardinals lost to Bears 28-13

STREAKS, STATS AND NOTES - 49ers can clinch NFC West for second straight season with win or Seattle loss against St. Louis. If 49ers win and Green Bay loses at Minnesota, San Francisco will earn No. 2 playoff seed and first-round bye. If 49ers lose and Seattle wins, San Francisco will be wild-card team and head on road for first round. ... Arizona has lost 10 of last 11 games. ... Bryan Hoyer will be fourth different quarterback to start for Cardinals this season. ... Aldon Smith needs three sacks to equal Michael Strahan's single-season record of 22 1/2 set with New York Giants in 2001. Smith has not had sack in consecutive weeks for first time this season. ... Michael Crabtree is 67 yards shy of becoming San Francisco's first 1,000-yard receiver since Terrell Owens (1,102) in 2003. ... 49ers 7-0 following loss or tie under coach Jim Harbaugh. ... Alex Smith completed 18 of 19 passes for 232 yards and three touchdowns in San Francisco's 24-3 rout at Arizona on Monday Night Football on Oct. 29. Smith has since been replaced by Colin Kaepernick, who is 4-2 as starter. ... Larry Fitzgerald caught eight passes for 111 yards in Arizona's 28-13 loss to Chicago last week. It was first time since Sept. 23 against Philadelphia he broke century mark. Fitzgerald had 89 yards receiving in last five games combined. He has 69 receptions for 785 yards. ... 49ers DL Justin Smith missed last week's loss at Seattle with elbow injury, snapping streak of 185 straight starts. He is not expected to play Sunday. ... 49ers K David Akers has made at least one field goal in 32 consecutive games. That's second-longest streak in NFL history behind Matt Stover, who had 38-game streak with Baltimore from 1998-2001.