Sopoaga returns, Jacobs still sits

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SAN FRANCISCO -- Running back Brandon Jacobs will have to wait at least another week to make his 49ers debut.Meanwhile, nose tackle Isaac Sopoaga will be back in uniform after missing one game with left knee and ankle sprains.Jacobs practiced all week for the 49ers, who could not find a way to make him one of the team's 46 active players. Jacobs, who signed a one-year, 1.575 million contract as a free agent, does not play special teams.Now, Jacobs potentially could make his 49ers debut next Sunday against his former team, the New York Giants.The 49ers have no lineup changes. For the Bills, Chris Hairston starts at left tackle for Cordy Glenn, and Chad Rinehart starts at right guard for Kraig Urbik. Both Glenn and Urbik are out with ankle injuries.
49ers inactives
QB Scott Tolzien
WR A.J. Jenkins
RB LaMichael James
S Trenton Robinson
RB Brandon Jacobs
G Joe Looney
NT Ian WilliamsBills inactives
QB Tavaris Jackson
RB Johnny White
SS Delano Howell
OLB Kirk Morrison
RG Kraig Urbik
LT Cordy Glenn
DT Spencer Johnson

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