GREEN BAY, Wis. (AP) — Aaron Rodgers threw for a career-high 480 yards and four touchdowns and the Green Bay Packers used a big first half against the Washington Redskins to win their home opener 38-20 on Sunday.
Redskins quarterback Robert Griffin III threw for 320 yards and three second-half touchdowns. Pierre Garcon had 143 yards receiving and a touchdown.
But it was too little, too late after Washington (0-2) fell short again after being outplayed early for a second straight week.
James Jones had a career-high 11 catches for 178 yards. James Starks ran for 132 yards and a touchdown.
Green Bay (1-1) built a 24-0 lead by halftime and never looked back.
CHARGERS 33, EAGLES 30
PHILADELPHIA (AP) — Philip Rivers threw three touchdown passes to Eddie Royal, and Nick Novak kicked a 46-yard field goal with 7 seconds left, spoiling Chip Kelly's home debut.
Michael Vick threw for a career-best 428 yards and two touchdowns and ran for a score. But a porous Eagles defense couldn't stop Rivers all day.
He finished 36 of 47 for 419 yards, and the Chargers punted only once. They fumbled twice inside Philadelphia's 10 in the first half.
The teams combined for 1,150 total yards, including 539 for San Diego.
BEARS 31, VIKINGS 30
CHICAGO (AP) — Jay Cutler threw a 16-yard touchdown pass to Martellus Bennett with 10 seconds left.
Minnesota's Blair Walsh had just kicked a 22-yard field goal with 3:15 remaining when Chicago took over at its 34. Cutler, who led the Bears back from an 11-point deficit in a season-opening win over Cincinnati, struck again.
A 23-yard pass to Bennett along the sideline put the ball on the 16. Cutler then spiked the ball before connecting with Bennett in the front corner of the end zone. Chicago remained unbeaten under new coach Marc Trestman despite committing four turnovers.
Cutler completed 28 of 39 passes for 290 yards and three touchdowns. But he was also intercepted twice and got stripped by Jared Allen on a sack, leading to a 61-yard touchdown return for Brian Robison in the second quarter.
CHIEFS 17, COWBOYS 16
KANSAS CITY, Mo. (AP) — Alex Smith threw for 223 yards and two touchdowns, and the Kansas City defense held when it needed to in the fourth quarter.
Jamaal Charles ran for 55 yards and caught a touchdown pass for the Chiefs, who made new coach Andy Reid a winner in his home debut. The Chiefs also matched their victory total from all of last season by starting 2-0 for just the second time since 2005.
Dwayne Bowe's touchdown catch in the third quarter and Ryan Succop's 40-yard field goal early in the fourth gave the Chiefs a 17-13 lead. The Cowboys (1-1) answered with a deep march into Kansas City territory but had to settle for Dan Bailey's 53-yard field goal with 3:55 left.
The Chiefs offense never gave the Cowboys a chance to mount a winning drive.
TEXANS 30, TITANS 24, OT
HOUSTON (AP) — Rookie DeAndre Hopkins caught a 3-yard touchdown pass in overtime to cap Houston's comeback win.
With Andre Johnson out after being shaken up in the fourth quarter, Hopkins reached above Jason McCourty and pulled in the pass from Matt Schaub to give Houston the victory.
The Texans (2-0) needed a franchise-record 21-point comeback to win their opener at San Diego 31-28.
On Sunday, they charged back from an eight-point, fourth-quarter deficit against the Titans (1-1).
Arian Foster's 1-yard touchdown and 2-point conversion tied it at 24-24 with less than two minutes left.
Houston forced a punt and got within field goal range after that. But Randy Bullock's 46-yard field goal attempt bounced off the left upright to force overtime. It was his third miss of the day.
BILLS 24, PANTHERS 23
ORCHARD PARK, N.Y. (AP) — Rookie EJ Manuel hit Stevie Johnson for a 2-yard touchdown pass with 2 seconds left.
The touchdown capped a nine-play, 80-yard drive in which the first-round draft pick completed 6 of 8 attempts for 51 yards. Manuel also got help on third-and-6 from Carolina's 29, when Panthers linebacker Luke Kuechly was penalized for pass interference with 14 seconds left.
Two plays later, Manuel found Johnson alone in the left corner as Buffalo (1-1) bounced back from a 23-21 season-opening loss to New England.
The Panthers (0-2) lost yet another close game. They were coming off a 12-7 loss to Seattle last week and have now dropped to 2-14 in games decided by 7 points or less in two-plus seasons under coach Ron Rivera.
DOLPHINS 24, COLTS 20
INDIANAPOLIS (AP) — Ryan Tannehill threw for 319 yards and one touchdown, and the Dolphins defense held off yet another Colts comeback bid.
Charles Clay gave Miami the lead for good with a 1-yard TD run late in the third quarter. The Dolphins are 2-0 for only the second time since 2004.
Indianapolis (1-1) lost at home for the first time in 12 months and only the second time in Andrew Luck's brief NFL career.
Luck had the Colts positioned to rally yet again after reaching the Miami 23-yard line with 1:45 left in the game.
But this time, Luck threw three straight incompletions and then could not evade the Dolphins pass rush on fourth down, allowing Miami to run out the clock.
Tannehill finished 23 of 34.
Luck was 25 of 43 for 321 yards with one TD and one interception.
FALCONS 31, RAMS 24
ATLANTA (AP) — Julio Jones hauled in 11 passes for 182 yards, including an 81-yard touchdown, and Atlanta held on for its first win of the season.
Matt Ryan threw for 374 yards and two scores despite taking quite a beating behind the Falcons' shaky offense line. Jason Snelling clinched it for the Falcons (1-1) with an 11-yard touchdown run with 6:18 remaining — Atlanta's longest play of the day on the ground.
The Rams (1-1) fell behind 21-0 when Osi Umenyiora returned an interception 68 yards for a touchdown early in the second quarter. Atlanta led 24-3 at halftime before St Louis fought back on a pair of short touchdown passes by Sam Bradford.
Bradford finished with 352 yards and three TDs.
RAVENS 14, BROWNS 6
BALTIMORE (AP) —Baltimore sacked Brandon Weeden five times before finally knocking him out of the game in the fourth quarter.
After yielding 49 points in a season-opening loss at Denver, Baltimore's defense came up with a redemptive performance against the Browns (0-2). Cleveland failed to score in the second half and managed only 85 yards over the final 30 minutes.
Weeden left with a thumb injury with just over three minutes left and was replaced by Jason Campbell, who could not move the team.
Down 6-0 at halftime, the Ravens (1-1) took the lead on a 5-yard run by Bernard Pierce with 5:13 left in the third quarter. Baltimore added a touchdown with 8:77 remaining on a 5-yard pass from Flacco to rookie Marlon Brown.
Ravens running back Ray Rice left early in the fourth quarter with an apparent hip injury.