The Giants led 4-2 after four but the Mariners tied it with two in the fifth, and added three runs in the sixth with some help from poor Giants defense, en route to a 7-4 Seattle victory.
The Giants will have their best defensive team behind Tim Lincecum Saturday night, with Joaquin Arias at third base, Brandon Crawford at short and Pablo Sandoval as the designated hitter.
SEATTLE Brandon Belts friends and family have T-shirtsthat say, Keep Belt awkward.
His teammates understand just what that means.
Ryan Vogelsong came out of his ritualistic blood fever, which he enters in the hours before every start, to say a rare word to a teammate Friday afternoon. It was to Matt Cain, aka, "the big man."
Buster Posey started the scoring with a solo shot in the second inning, Melky Cabrera followed suit with a two-run homer in the eighth, and Ryan Vogelsong was spectacular again as the Giants beat the Mariners 4-2.
Justin Christian is back in the big leagues with his hometown team. Hes an energetic outfielder who never stops moving.
Tim Lincecum never sits still in the dugout. So he watched Matt Cains perfect game unfold from every angle in the dugout Wednesday night.
Lincecum said he is not soliciting pitching advice from his father, Chris, who had been his coach his whole life and worked to develop the gymnastic mechanics that allowed him to generate such power from his smallish frame.
Ryan Volgesong gets the call for the Giants when they open their series against the Mariners in Seattle. Andrew Baggarly looks ahead. More: Vogelsong 5-2 vs. Vargas 7-5 MLB standings
Hot-hitting Fresno outfielder Justin Christan was removed from Grizzlies roster and is expected to take Aubrey Huff's place with the Giants as Huff recovers from a knee injury.
He credited catcher Buster Posey first, and right fielder Gregor Blanco, and perfect pitcher Matt Cain also took a moment to acknowledge the man perched behind Poseys shoulder.
Brandon Belt may starting to feel smooth on field, but he was anything but when he took a seat in the dugout in the seventh inning.
Dave Righetti is a pitching coach. He teaches his starters and relievers how to harness their stuff. He knows something about the stuff inside, too.
Blanco provided the impossible catch. In a recipe for a perfect game, thats the leavening agent. But Matt Cains perfect night included two other dashes of fate Wednesday night.
Matt Cain struck out 14 batters on an unforgettable Wednesday night in China Basin. It matched Sandy Koufaxs iconic performance in 1965 as the most strikeouts in a perfect game in history.