SANTA CLARA -- Linebacker Darius Fleming, who missed all of his rookie season with a torn ACL in his left knee, appeared to re-injure the knee during a 7-on-7 passing drill Tuesday.
Fleming remained on the ground for several minutes before getting up under his own power. He dropped into coverage against tight end MarQueis Gray when he turned to find the ball. He landed awkwardly after jumping.
He tried to get up but went back to the ground. After several moments, he was able to get up under his own power. He walked around with 49ers head trainer Jeff Ferguson and was seen flexing his left knee. He remained on the field to watch practice.
Fleming sustained his season-ending injury a year ago during the team's rookie camp in May. He was a fifth-round draft pick from Notre Dame.
Coach Jim Harbaugh is scheduled to speak with the media after practice at 2:30 p.m. He should be able to provide an update on Fleming's condition.
--Veteran center Jonathan Goodwin made his first appearance in the offseason program, as he was on the practice field at the beginning of Tuesday's practice.
--Wide receiver Anquan Boldin was not in attendance at the beginning of practice.
--Running back LaMichael James took part in individual work and caught kickoffs, but he was not taking part in practice. Tight end Cameron Morrah left the practice field with an apparent left muscle strain.
--Others who were not practicing: Michael Crabtree (Achilles), Frank Gore (undisclosed), Carlos Rogers (undisclosed), Tarell Brown (does not attend voluntary workouts), Donte Whitner (undisclosed), Marcus Lattimore (knee), Ahmad Brooks (shoulder), Justin Smith (triceps), Aldon Smith (shoulder), Joe Staley (knee), Mike Iupati (shoulder), Tank Carradine (knee), Quinton Dial (toe) and Luke Marquardt (foot) Kendall Hunter (Achilles) Kyle Williams (knee), Mario Manningham (knee).
--Newly signed safety Raymond Ventrone was seeing action at slot receiver.
--Former New York Jets and Cleveland Browns coach Eric Mangini was on the field in his new role as 49ers senior offensive consultant.