The 49ers on Friday rolled out of Santa Clara on a two-game, 10-day, nine-night road trip that'll take them to Cincinnati, Youngstown, Ohio, and Philadelphia.
In the offseason former 49ers Nate Clements and Manny Lawson took their talents to Cincinnati. Both players have a chance to beat their former team on Sunday and will be involved in key matchups.
Receiver Michael Crabtree is expected to return to the 49ers' lineup Sunday against the Cincinnati Bengals after missing a game with a left foot injury.
Jim Harbaugh confirms the news that rookie backup QB Colin Kaepernick saw an increase in practice time, a response to the injury incurred by Alex Smith.