The 49ers on Friday rolled out of Santa Clara on a two-game, 10-day, nine-night road trip that'll take them to Cincinnati, Youngstown, Ohio, and Philadelphia.
In the offseason former 49ers Nate Clements and Manny Lawson took their talents to Cincinnati. Both players have a chance to beat their former team on Sunday and will be involved in key matchups.
Receiver Michael Crabtree is expected to return to the 49ers' lineup Sunday against the Cincinnati Bengals after missing a game with a left foot injury.
Jim Harbaugh confirms the news that rookie backup QB Colin Kaepernick saw an increase in practice time, a response to the injury incurred by Alex Smith.
Dashon Goldson will be active for the first time this season and expects to replace veteran Madieu Williams in the 49ers' lineup. Goldson: "I'm expecting to start."
The percentages say at some point the 49ers will need their rookie QB to perform. He said hes ready for that chance.
Greg Roman, the 49ers' offensive coordinator, has a unique history with the Cincinnati Bengals. Remember Super Bowl XXIII?
Just prior to Tony Romo's 53-yard second-quarter TD pass to Austin Miles, officials flagged 49ers LB Ahmad Brooks for being offsides. The problem? He wasn't.
Alex Smith: "Feel great. Went through all the protocol that the league requires and doctors require. Everything looks great. Ready to play."
The 49ers traded up to No. 36 to select Colin Kaepernick, after the Bengals chose Andy Dalton at No. 35. It's now clear Jim Harbaugh wouldve been happy with either quarterback.
Alex Smith was likely hurt on the first play of the second quarter on hits by Dallas LB Anthony Spencer and CB Alon Ball.
Alex Smith received full medical clearance to participate in 49ers practice Wednesday after sustaining a concussion in the 49ers' loss to Dallas.
Even with Braylon Edwards expected to miss several weeks after undergoing an arthroscopic procedure on his right knee, the 49ers still do not feel a pressing need to add another wide receiver.
Tight end Vernon Davis expressed surprise at Jim Harbaugh's game plan following the overtime loss to the Dallas Cowboys. This week, the coach and the player talked it out.