Crabtree decided to forgo his remaining two seasons in college to enter the NFL Draft. He left college with eight NCAA records. On Feb. 21, 2009, Crabtree sustained a fracture in his left foot. He had surgery on the leg after the Combine, but before Texas Tech's Pro Day. He was selected No. 10 overall by the 49ers. Crabtree held out of Training Camp because he lacked a contract. On Oct. 7, 2009 Crabtree agreed to a six-year contract worth $32 million. The first-rounder played in 11 games, catching 48 passes for 625 yards and two touchdowns as a rookie.