Raiders running back Darren McFadden will miss his second straight game with a lingering foot injury, according to the NFL Network.
Michael Fabiano tweeted Tuesday afternoon that McFadden will not play against the Chargers.
The Raiders play on short rest Thursday in San Diego, where head coach Hue Jackson will lean on Michael Bush and Taiwan Jones, as he did last Sunday against the Broncos. In McFadden's absence, Bush ran for 96 yards on 19 carries while Jones only rushed twice for one yard.
McFadden was leading the league in rushing heading into the Raiders' game against Kansas City on Oct. 23 but could not finish the contest.
For the season, the 4th overall pick in 2008 has 113 carries for 614 yards and four touchdowns. He also has caught 19 balls for 154 yards and another touchdown.