Alex Smith speaks with reporters about throwing passes to future Hall of Famer Isaac Bruce in the last game of his career.

The big day for the wide receivers. Yeah well because. Mike Singletary mentioned it and Isaac Bruce had touched on is well outside the ten and it's. The fact that players in this locker room lobbied to see him get an opportunity …

Isaac Bruce speaks to reporters about ending his career against the Rams in St Louis.

… things got there and and I do my job offense go and do our job together as a unit and a this game. More than likely Isaac Bruce has played his final game for the 49ers as a wide receiver will not be active for the final two games of this season …

… this receiving corps as tight end and what you saw specifically that second half. that we have as Morgan Jason Hill. Isaac Bruce Baron Davis. Right they coming out this aspect is that kids Frank Gore certainly got a lot of witnesses this about …

Isaac Bruce talks with reporters about relinquishing his starting WR role to Josh Morgan.

… Scott McClure is gonna join us live from a candlestick it very simply Scott ask you first about your wide receiver. Isaac Bruce who was at a tender ankle for weeks in many. Aggravated in the game against Tennessee on Sunday and also re aggravated …

Happy Birthday Isaac Bruce ! On his 37th birthday, Bruce spoke to CSN's Mindi Bach on Tuesday.

Listen carefully to 49ers' soft-spoken WR Isaac Bruce say that Michael Crabtree's presence on the field makes it better for the other offensive players.

… t know whether Michael Crabtree will start tomorrow or not but here's something not to be overlooked tomorrow is Isaac Bruce 200 start. In his sixteen year career Bruce led the 49ers in receiving last year he has faced the Texans only once …

… I mean this the doesn't have to be just a smash power running offense we've got a lot of play makers. You know Isaac Bruce and Vernon walker I mean this is an office we can move the ball down through their playmakers and they stepped up today …

… seven and a half and it. Time and we controlled the clock you're able to really mix up the ball the past he passes Isaac Bruce and Vernon Davis wet was the decision to get away from Iran and kind of open at this field a lot of it. Well I don …

What are you seeing from the passing game from show on the and Alex and Isaac Bruce and Morgan and some of the younger wide receivers so far why I think more importantly Vernon you know Vernon as a great job I think …

… don't read into that he did indicate that Alex has some reps as well. Any that led will start and Frank Gore and Isaac Bruce we'll sit this one out. Sound you'll. You'll start to game. Do not know who'll start next week. In relief …

… Willis is also listed as a starter he had run drills and first day of practice. With that ankle sprain Josh Morgan Isaac Bruce listed as receivers one into. Glen Coffee is the backup running back meaning you'll see plenty of time the season …

… Crabtree all that still no end in sight. With Crabtree out of the mix and Brandon Jones answered the niners have listed Isaac Bruce and Josh Morgan. As the first string wide outs in the official game knowledge or Friday's free season opener. With …

… now the matching it is pretty extensive getting better pat Willis. Just mention now that ankle injury reverend Ike Isaac Bruce we got Bo Diddley died Monday but is not. Considered a big injury and fullback Moran Norris was excused from camp for …

Isaac Bruce held a rare impromptu Q&A with reporters during Saturday's OTA at 49ers' camp in Santa Clara. The reclusive WR shared his thoughts on coming back for his 16th season and being reunited with former teammate, CB Dre Bly.