SANTA CLARA -- When discussing the two quarterbacks who will be on the field Sunday at Candlestick Park, 49ers coach Jim Harbaugh described Eli Manning of the New York Giants and Alex Smith in much
SANTA CLARA -- The 49ers have played the New York Giants three times since Alex Smith's rookie season, but Smith has never been on the field for any of those games due to injuries.
First-half storyline: The 49ers have only four defensive players back at the same starting position from a year ago. And each of the changes has been for the better.
SANTA CLARA -- Defensive end Ray McDonald's status for the 49ers' game on Sunday against the Washington Redskins remains uncertain.McDonald sustained a left hamstring strain in the second