Isaac Sopoaga

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SANTA CLARA -- Guard Mike Iupati did not practice Wednesday due to a left knee injury, as the 49ers began their week of work to get prepared to face the unbeaten Detroit Lions on Sunday.Iupati'

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SANTA CLARA -- Nose tackle Isaac Sopoaga returned to the 49ers' practice field Wednesday, but left guard Mike Iupati was an onlooker during the early portion of 49ers practice.Sopoaga was not

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SANTA CLARA -- Receiver Joshua Morgan's contract expires at the end the season.

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SANTA CLARA -- Nose tackle Isaac Sopoaga, who missed Sunday's game due to a staph infection, was spotted leaving the 49ers' practice facility Monday morning with his left arm in a sling.T

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For the first time in his career, quarterback Alex Smith was removed from a game because of success.

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