OPENING LINE - Cardinals by 8
RECORD VS. SPREAD - Cardinals 6-4, 49ers 4-6
Alex Smith lost his 49ers starting job – through no fault of his own – three years ago.
Stephen Curry is the reigning MVP and is arguably the best basketball player on the planet.
SANTA CLARA – The 49ers’ red-zone offense was among the worst in the NFL last season. It was seen as an obvious area in which the team could improve this season.
Colin Kaepernick was benched in favor of Blaine Gabbert, who started the past two games for the 49ers.