EUGENE, Ore. (AP) Anthony Brown scored a career-high 24 points and Stanford held on to send No. 17 Oregon to its third straight loss, 82-80 on Sunday.
Chasson Randle had 23 points for the Cardinal (10-5, 1-2 Pac-12), who beat their second ranked team this season, something they hadn't accomplished since 2009.
Mike Moser scored 24 points to lead the Ducks (13-3, 1-3), who had two chances to tie the game in the final 8 seconds but Johnathan Loyd missed an open jumper and Dominic Artis had a last-ditch layup roll off the rim as time expired.
Oregon opened the season 13-0 but hasn't won since beating Utah in overtime on Jan. 2. The Ducks have since lost to No. 15 Colorado, California and the Cardinal. They have allowed an average of 92.6 points in those games.
Brown made his first seven attempts from the field and 10 of 12 overall. Randle, who was coming off a 30-point performance in a loss to Oregon State in Thursday, was 8 of 14 from the field.
Stanford led 41-37 at halftime and didn't lose the lead in the second half, though Oregon pulled within two points following 3-pointers on four straight possessions - three by Moser - that made it 64-62 with 11:38 to play.
The Ducks again cut their deficit to one possession following a jumper by Loyd that made it 77-74 with 2:12 to play, but Brown answered with a long jumper.
Dwight Powell had 14 points and six assists for the Cardinal.
Jason Calliste had 12 points and Damyean Dotson scored 10 for Oregon.
The Ducks hit nine of their first 15 shots to take a 27-21 lead with 7:19 to play in the half.
But Brown, who scored 13 points in the first half, hit a short jumper and then scored in transition off a turnover to spark a 10-2 run that put the Cardinal up 31-29 and they eventually pushed their lead 41-37 at halftime.
Oregon made just one field goal in the final 8:38 of the half and committed 11 turnovers in the first half that resulted in 14 points for Stanford.
Randle scored 14 points in the first half. His layup with 1:13 to play gave the Cardinal their largest lead of the half, 41-34.