OPENING LINE - Cardinals by 8
RECORD VS. SPREAD - Cardinals 6-4, 49ers 4-6
SANTA CLARA – Arizona Cardinals defensive back Tyrann Mathieu won NFC Defensive Player of the Week based on his mastery of the 49ers’ offense earlier this season.
SEATTLE -- Arizona Cardinals offensive lineman Mike Iupati was taken off the field in an ambulance Sunday night after a collision while making a block in the second quarter agai