Mario Manningham

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SANTA CLARA -- Wide receiver Mario Manningham will miss his second postseason with the 49ers, as the club placed him on injured reserve Friday.

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SANTA CLARA – Wide receiver Mario Manningham, who sat out the 49ers’ game Monday night with a sore knee, did not practice Thursday.

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SAN FRANCISCO – Pro Bowl guard Mike Iupati will return to the 49ers’ starting lineup Monday night after missing four games with a knee injury.

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Programming note: Immediately following the conclusion of Monday night's 49ers-Falcons game, change the channel to CSN Bay Area for 49ers Postgame Live. 

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SANTA CLARA – Guard Mike Iupati, who has missed four games with a partially torn knee ligament, remains questionable for the 49ers’ game Monday night against the Atlanta Falcons.

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