Patrick Willis

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Programming note: Not near a TV on Sunday? Cat

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SANTA CLARA -- The 49ers’ defensive linemen have to be on their toes – and watching their ankles – on Sunday night against the Houston Texans.

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Programming note: Watch Thursday's 49ers press conference with Vic Fangio, Greg Roman and Frank Gore streaming LIVE at 12

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The difficult part is over for the 49ers after reaching the one-quarter point of the season with a 2-2 record.

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ST. LOUIS – The 49ers will attempt to snap the first two-game losing streak under Jim Harbaugh without All-Pro linebacker Patrick Willis.

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